Hello - great set of tools, extremely useful.
I was hoping to try using SOLO for doublet detection and can see this is now incorporated into scvi tools.
I’m not finding the usage of this particularly clear.
Seems that the guidance is that it should be run on a single droplet sequencing lane at a time, and it’s not possible to run after training an scvi model with batch correction. Is that correct?
After training then predicting I am getting a numpy array which is a little difficult to interpret - the dimensions are larger than the original anndata object - so perhaps it is the simulated doublets and the native cells together. It’s just a little unclear.
Any chance you could clarify how best to use this tool?